ingwer immunsystem studie

Denn eine Schlüsselrolle bei der positiven Wirkung spielen Scharfstoffe, allen voran die sogenannten Gingerole. Kashefi F., Khajehei M., Alavinia M., Golmakani E., Asili J. Bax, Bcl-2, p21, hTERT, MIB-1, Bax/Bcl-2 Ratio, Bax/hTERT Ratio, Bax/MIB-1 Ratio, p21/hTERT Ratio, p21/MIB-1 Ratio, cell cycle score (w/MIB-1), and cell cycle score (w/hTERT), Two grams of ginger extract may help in reducing the proliferation of normal-appearing colorectal epithelium, as well as increased apoptosis and differentiation relative to proliferation—especially in the differentiation zone of crypts, PGE2, 13-hydroxy-octadecadienoic acid, and 5-, 12-, and 15 hydroxyeicosatetraenoic acid. Hierbei helfen Ihnen unsere einfachen Hausmittel! Um mehr über die Effekte einzelner Lebensmittelinhaltsstoffe auf die Speichel-Zusammensetzung zu erfahren, haben Wissenschaftler des Leibniz-Instituts für Lebensmittel-Systembiologie in München verschiedene Geschmacksstoffe untersucht, darunter das in Ingwer enthaltene 6-Gingerol (scharf) und Zitronensäure (sauer). In der traditionellen chinesischen Medizin spielt Ingwer seit Jahrhunderten eine große Rolle. Four RCTs examined the anticancer effect of ginger, all of which evaluated the risk of colorectal cancer according to the ginger treatment. However, an obvious limitation is that all studies were performed in a sample size of fewer than 50 participants. The health-promoting perspective of ginger is attributed to its rich phytochemistry. The thermogenetic function of ginger was examined by three randomized crossover trials, and only one study observed the expected outcome. Ingwer und Zitrone gelten seit langer Zeit als beliebte Hausmitteln bei Erkältungen. ); rk.ca.uns@0113dudlmd (E.Y.S. Tipps von Immunspezialist Dr. Thomas Rampp, Abwehrkräfte stärken, Erkältungssymptome lindern. So unterstützen aus Ingwer gewonnene Extrakte unabhängig von einer Insulingabe die Aufnahme von Glukose in Muskelzellen, die bei Typ-2-Diabetes aufgrund einer gestörten Insulin-Signalübertragung reduziert ist. A double blind randomized controlled pilot trial. Anti-inflammatory and antioxidant effect of ginger in tuberculosis. Therefore, further studies with larger sample sizes and standardized study designs should be conducted to confirm the effect of ginger on the symptoms of OA. Data were collected up to July 2019 and regularly updated by manual search. 1. Der belarussische Machthaber Alexander Lukaschenko bringt flüchtende Menschen an die Grenze zur EU. Jedoch ist die von den Forscher:innen für die Inkubation eingesetzte [6]-Gingerol-Konzentration nicht aus der Luft gegriffen, sondern an die mittlere maximale Plasmakonzentration angelehnt, die in einer vorausgegangenen Forschungsarbeit bei Proband:innen nach dem Konsum von einem Liter Ingwertee gemessen wurden (42 nmol/L). Additionally, lipid profiles (e.g., total cholesterol, and LDL-C), C-reactive protein, obesity-related cardiovascular risk factors have been found to reduce with ginger intake [24,88,89,90]. An official website of the United States government. concluded that ginger is more effective in relieving the severity of nausea compared to vitamin B6 (p = 0.024) [3]. Ingwer wirkt entzündungshemmend, aktiviert die Darmtätigkeit und war in Laborversuchen gegen verschiedene Viren wirksam. Langfristig können Geschmacksstoffe, indem sie die Produktion von wichtigen Enzymen im Speichel anregen, einen wichtigen Beitrag leisten unser Immunsystem zu stärken. Firstly, for English literature, we searched Pubmed, EMBASE, Cochrane Central Register of Controlled Trials (CENTRAL), and Clinical Trials (ClinicalTrial.gov) with the query: “Zingiber officinale” OR “Z. Aktuelle Berichte, News und Beiträge zu Themen aus Politik, Wirtschaft, Finanzen, Umwelt und Wissenschaft in Deutschland, Europa und der Welt bei deutschlandfunk.de. Ingwer ist reich an ätherischen Ölen. A daily dosage of 0.5–1.5 g of ginger was frequently adopted, while six studies treated ginger with a multiple dosage range (Figure 2e). Kann man Krankheiten rein durch richtige Ernährung heilen? Paritakul P., Ruangrongmorakot K., Laosooksathit W., Suksamarnwong M., Puapornpong P. The effect of ginger on breast milk volume in the early postpartum period: A randomized, double-blind controlled trial. Hinweise auf positive Effekte auf das Immunsystem gibt es schon lange – bisher war jedoch nicht klar, welcher Mechanismus dahintersteckt und ob normale Ingwermengen überhaupt reichen, um die Abwehr zu stimulieren. Kein Problem! Regarding obesity, the included study targeted the effect of ginger on obesity. Ginger effectively reduced the duration of mechanical ventilation and the length of stay in the intensive care unit in ARDS patients; it also improved asthmatic symptoms. Effect of ginger root on cyclooxygenase-1 and 15-hydroxyprostaglandin dehydrogenase expression in colonic mucosa of humans at normal and increased risk for colorectal cancer. Tatsächlich fördern bestimmte Inhaltsstoffe die Immunabwehr im Speichel, wie eine neue Untersuchung zeigt. This study focused on randomized clinical trials investigating the efficacy of ginger to improve human health as well as to support human disease. Zumindest hat man im Labor bei Experimenten beobachtet, dass Ingwerextrakt krebshemmend wirkt bei Krebszellen, die man im Reagenzglas züchtet. Gesundheitsstadt Berlin hat mit PD Dr. Michael Schumann über die Auslöser und Folgen der Autoimmunerkrankung gesprochen. Es ist nicht ganz so zuverlässig, also wir haben beim Ingwer immer mal doch auch so genannte Nonresponder, wo es nicht so wirkt. proposed that benefits of ginger were observed due to a reduction in the level of the proinflammatory cytokines after three months of consuming 500 mg of ginger powder [13]. Mahluji S., Attari V.E., Mobasseri M., Payahoo L., Ostadrahimi A., Golzari S.E. Doch nicht immer. Patienten, die blutverdünnende Medikamente nehmen, sollten daher wissen, dass Ingwer, frisch und reichlich genossen, ebenfalls die Gerinnung hemmt. In addition, ginger was suggested to have antioxidant and anti-dysmetabolic effects in obese women with breast cancer. Weitere Indikationen sind die symptomatische Behandlung milder Magen-Darm-Beschwerden (HPMC 2012, traditional use) und postoperatives Erbrechen nach kleineren Eingriffen (ESCOP 2009). Matthias Melzig meint dazu: "Vorsichtig sollte man immer sein, wenn man in der Schwangerschaft Arzneimittel einnimmt, aber wenn man das bestimmungsgemäß tut, also soviel nur nimmt, wie empfohlen wird, dann denk ich, besteht keine Gefahr.". In diesem Tee steckten 100 Gramm chinesische Ingwerknolle, geschält und zerkleinert – das ist eine erhebliche Menge. Bei den Probandinnen und Probanden ließ sich nach dem Konsum der Scharfstoff [6]-Gingerol im Blutplasma nachweisen. reported that ginger supplementation alone and combined with antitubercular treatment significantly helped to decrease tumor necrosis factor (TNF) alpha, ferritin, and malondialdehyde (MDA) levels compared to the control group [67]. All authors have read and agreed to the published version of the manuscript. Phillips S., Ruggier R., Hutchinson S.E. and fenugreek (Trigonella foenumgraecum L.) on blood lipids, blood sugar and platelet aggregation in patients with coronary artery disease. This research was supported by the Rural Development Administration of Korea (PJ01420102). (b/Foto: pilipphoto / Adobe Stock). Bethesda, MD 20894, Web Policies Shidfar F., Rajab A., Rahideh T., Khandouzi N., Hosseini S., Shidfar S. The effect of ginger (Zingiber officinale) on glycemic markers in patients with type 2 diabetes. Karimi N., Dabidi Roshan V., Fathi Bayatiyani Z. Von Jürgen Herbers | Text und Audio dieses Beitrags stehen unter der Creative-Commons-Lizenz CC BY-NC-ND 4.0. Schon der Gedanke an Essen reicht und es läuft uns das Wasser im Mund zusammen. Ginger (Zingiber officinale) reduces muscle pain caused by eccentric exercise. The https:// ensures that you are connecting to the Angebaut wird dieser hauptsächlich in Südchina, aber auch aus Martinique, Jamaika und Australien wird Arzneiingwer importiert. Dazu werden dünne Scheiben der rohen Wurzel 10 Minuten in heißem Wasser gekocht und diese Flüssigkeit sofort getrunken. Arzneiingwer enthält 1,5 – 3 Prozent ätherisches Öl und 1–2 Prozent nichtflüchtige Scharfstoffe wie Gingerole. In knee osteoarthritis patients, serum TNF-αNF-m IL-1β was decreased in both groups, with a lower level in the ginger group than the placebo group. and Martins et al. The ginger treatment group decreased vomiting at anticipatory, acute, and delayed phases of patients who received chemotherapy. concluded that ginger showed an insufficient effect on the prophylaxis of acute and delayed nausea and vomiting induced by an Adriamycin–cyclophosphamide regimen and a cisplatin regimen, respectively, which are highly emetogenic regimens [19,20]. Rhodes index of nausea, vomiting, and retching. Collectively, no major function satisfied the criteria for every study except colorectal cancer. sharing sensitive information, make sure you’re on a federal Ginger treatment showed significantly greater relief on hyperemesis than a placebo. However, only one out of 46 patients (2.17%) reported the symptom, indicating no statistically significant correlation to ginger [28]. Am 1. Inappropriate articles were excluded for the following reasons: (1) not clinical trials; (2) not related topic; (3) irrelevant data for analysis; (4) secondary analysis; (5) unavailable abstract or full-text; (6) duplication; and (7) case reports, letters, commentaries, meeting records, or review articles. Mittlerweile soll Zucker schuld sein an Übergewicht, Diabetes und Herz-Kreislauf-Erkrankungen. In others, the emphasis is on host-parasite interactions and the parasite as a disease-causing entity. ); rk.ca.uns@40mikmhuns (H.M.K. It is the major class of the five classes of immunoglobulins in human beings, IgM, IgD, IgG, IgA, and IgE. Wie schon Paracelsus sagte, es ist die Dosis, die die Arznei vom Gift unterscheidet. Furthermore, ginger has been used as an herbal medicine for common health problems. After one week, the severity of nausea and vomiting was reduced dramatically in 60.6%, 42.7% and 61% of the ginger, placebo, and B6 groups, respectively. Serum FBG, HbA1c, insulin, HOMA, QUICKI, TG, TC, LDL-C, HDL-C. Ginger supplementation had a significant effect in reducing the levels of insulin, LDL-C, TG, and HOMA, and it increased the QUICKI index compared to the control group. Ensiyeh J., Sakineh M.-A.C. Prospective comparative study of the safety and effectiveness of ginger for the treatment of nausea and vomiting in pregnancy. Phase II trial of encapsulated ginger as a treatment for chemotherapy-induced nausea and vomiting. Viele Patienten fühlen sich auch matt und abgeschlagen, einige leiden unter Kopf- oder Gliederschmerzen. Dazu werden dünne Scheiben der rohen Wurzel 10 Minuten in heißem Wasser gekocht und diese Flüssigkeit sofort getrunken. Noticeably, several studies compared the effectiveness of ginger with other anti-inflammatory drugs. Das Spektrum der Stoffe deckte alle möglichen Geschmackserlebnisse ab: Saure Zitronensäure, bittere Iso-alpha-Säuren, salziges Kochsalz, süßen Aspartam und sogar den berüchtigten fünften Geschmacksinn umami. Incidence of nausea, dry retching, and vomiting (by Rhodes index of nausea and vomiting form) and health status (by MOS 36 short form health survey), Pregnant women with nausea, dry retching, vomiting can use ginger in the early stage of pregnancy to relieve the severity of symptoms as effectively as vitamin B6, The severity of dysmenorrhea, nausea, and vomiting (by VAS), average of nausea spells per day, vomiting episodes, average of nausea episodes, and average number of vomiting in last week. There were significant differences in the severity of pain between the two groups, but only ‘protocol 1’ showed a significant difference in the duration of pain between two groups. Weiterhin exprimierten die Zellen in der Folge vermehrt bestimmte Oberflächenproteine wie FPR1 (Formyl peptide receptor 1). Sanaati F., Najafi S., Kashaninia Z., Sadeghi M. Effect of ginger and chamomile on nausea and vomiting caused by chemotherapy in Iranian women with breast cancer. Moreover, no serious adverse effects were observed in all included studies. Apariman S., Ratchanon S., Wiriyasirivej B. After a systematical search that selectively focused on the study design of the clinical trials, we retrieved 221, 222, 59, and five papers from PubMed, Embase, Clinical Trials, and CENTRAL, respectively. As demonstrated by our assessment on reporting quality, attrition bias, and reporting bias were observed to be minor in a majority of studies, and the blinding of participants was also relatively well managed. Am Mobilgerät tippen Sie auf die einzelnen Punkte. Thirty-one papers with low risk on this item described the blinding of the data analyzer or stated that their study design was triple-blinded. Chen C.X., Barrett B., Kwekkeboom K.L. Und tatsächlich konnten Forscher das jetzt wissenschaftlich untermauern -an menschlichem Speichel. There is no significant difference in average risk for CRC between the ginger and placebo groups. Episodes of vomiting and nausea severity by nausea and vomiting grading. Zick S.M., Ruffin M.T., Lee J., Normolle D.P., Siden R., Alrawi S., Brenner D.E. The workflow of this study is shown in Figure 1. In particular, Chen et al. Prof. Dr. Andreas Michalsen, Chefarzt am Immanuel Krankenhaus Berlin und Professor für Klinische Naturheilkunde an der Charité, über die Grenzen der Schulmedizin, den Wildwuchs in der Naturheilkunde und warum sich beide Disziplinen gerade näherkommen. Danwilai K., Konmun J., Sripanidkulchai B.-O., Subongkot S. Antioxidant activity of ginger extract as a daily supplement in cancer patients receiving adjuvant chemotherapy: A pilot study. Lien H.C., Sun W.M., Chen Y.H., Kim H., Hasler W., Owyang C. Effects of ginger on motion sickness and gastric slow-wave dysrhythmias induced by circular vection. GGT has been proved to have antiviral activity against human respiratory syncytial virus (HRSV). Taking ginger as a reduction of CINV was insufficient, and there was no additional benefit for reducing the severity of acute and delayed CINV. Ginger (Zingiber officinale Roscoe), a well-known herbaceous plant, has been widely used as a flavoring agent and herbal medicine for centuries. „deftig-herzhaft und ein bisschen nach Brühwürfel“, Ballaststoffreiche Lebensmittel (Tabelle), NADH – Das wichtigste Molekül für unseren Körper, 9 Expertentipps für mehr Bewegung im Alltag, Darum solltest du Kraft- und Ausdauertraining kombinieren. A single 2 g dose of ginger did not attenuate eccentric exercise-induced muscle pain, inflammation or dysfunction at 45 min after ingestion. After the crossover (three months), the ginger treatment group showed a significantly higher effect compared to the placebo group. The effects of pre-exercise ginger supplementation on muscle damage and delayed onset muscle soreness. However, the comparison group in this study managed dysmenorrhea with exercise instead of a placebo or other medication, thus giving a high risk of confounding factors. For better visualization, a methodological quality graph is introduced in Figure 3. Ginger shots are made from concentrated amounts of ginger and are popular in the health community. Nicht jeder möchte jedoch sofort zu starken Medikamenten greifen. Ultimately, the overarching goal of these disciplines is to facilitate the . Ginger (Zingiber officinale Rosc.) Subsequently, 101 duplication records were eliminated. Regarding metabolic diseases, many studies have demonstrated that ginger can improve blood biochemical parameters and lipid profiles, which can additionally help in reducing the risk of cardiovascular diseases. These organisms cause a wide array of important human and animal diseases worldwide. Bioactive compounds and bioactivities of ginger (Zingiber officinale Roscoe). Attrition bias and reporting bias were the two least potential biases that could interrupt the results of the included trials, where 101 and 103 studies were assigned to low risks of attrition and reporting bias, respectively. Members use a broad range of systems biology, molecular biology, structural biology, and genetic approaches to understand parasite biology and host-parasite interaction. Der Ingwer-Scharfstoff versetzt die Immunzellen also in einen „ready-to-go“-Status, sodass sie im Falle einer eintretenden Infektion stärker reagieren können. Tatsächlich fanden die Forscher:innen, dass mit [6]-Gingerol vorinkubierte Zellen auf einen fMLF-Reiz hin deutlich mehr Interleukin-8 sowie zur Erregerabwehr verwendete reaktive Sauerstoffspezies (ROS) freisetzten als nicht mit [6]-Gingerol behandelte Kontrollzellen. Immunology Graduate Group . Praktische Tipps standen nicht im Fokus der Untersuchung, aber Ingwer-Liebhaber sollten ein paar allgemeine Ratschläge beherzigen: Je feiner man die Knolle schneidet, desto mehr Scharfstoffe und ätherische Öle können sich lösen. "Liebe Bürgerinnen und Bürger", "Liebe Bürger:innen", "Liebe Bürger"? Zudem wurden der Süßstoff Aspartam (süß), Iso-alpha-Säuren (bitter), der Geschmacksverstärker Natriumglutamat (umami), Kochsalz (salzig), sowie die im Szechuanpfeffer enthaltenen Substanzen Hydroxy-alpha-Sanshool (kribbelnd) und Hydroxy-beta-Sanshool (betäubend) auf die Probe gestellt. Acids. Instead, factors of inflammation, proliferation, differentiation, and apoptosis were measured upon treatment with 1–2 g of ginger to evaluate the improvement of risk. Studien haben gezeigt, dass die Inhaltstoffe des Ingwers genau die Rezeptoren im Brechzentrum des Gehirns besetzen, die oft während einer Chemotherapie aktiviert werden. Alte Hausmittel wie die heiße Zitrone und Ingerwertee werden immer beliebter. cyclooxygenase-1 and 15-hydroxyprostaglandin protein levels. Weltweit gehen die Bestände von Tier- und Pflanzenarten dramatisch zurück. N/A: Not available. Bordia A., Verma S.K., Srivastava K.C. Federal government websites often end in .gov or .mil. reported that a single dose of 10 g of powdered ginger significantly reduced Adenosine diphosphate-induced and epinephrine-induced platelet aggregation in patients who were recovering from myocardial infarction [68]. Specifically, the major classes of ginger compounds are gingerol, shogaols, zingiberene, and zingerone, as well as other less common compounds, including terpenes, vitamins, and minerals [6]. Gonlachanvit S., Chen Y.H., Hasler W.L., Sun W.M., Owyang C. Ginger reduces hyperglycemia-evoked gastric dysrhythmias in healthy humans: Possible role of endogenous prostaglandins. Auf dieser Webseite kommen Cookies zum Einsatz. Members also regularly attend the UCLA MBI and I3T seminar series, as well as the Microbial Pathogenesis Seminar Series, hosted by the Microbial Pathogenesis Training Grant. Die Langzeitfolgen der Corona-Pandemie machen Beschäftigten in Gesundheitsberufen besonders zu schaffen. Ginger—An herbal medicinal product with broad anti-inflammatory actions. In terms of obesity-related cardiovascular risk factors, ginger was reported to be beneficial in lowering the risk factors, such as body fat mass, body fat percentage, total cholesterol, waist circumference, waist-to-hip ratio, and insulin resistance. conducted data quality checks, data synthesis, and data interpretation. Verschärft wird die Situation durch die Corona-Pandemie und abwandernde Pflegekräfte. All studies that observed gastric emptying rate reported ginger as a digestive enhancer, except the study from Phillips et al., where they denied the facilitation of gastric function as demonstrated by the paracetamol absorption rate [50]. Ingwer wirkt bei Blähungen. and Müzeyyen et al., where they concluded the antiemetic effect of ginger, were assessed to have a high risk of bias in the blinding of participants [75,76]. SWR2. Ansari M., Porouhan P., Mohammadianpanah M., Omidvari S., Mosalaei A., Ahmadloo N., Nasrollahi H., Hamedi S.H. Among them, gingerols are considered as the primary components, reported to possess several bioactivities [7]. Das sei ein erfreuliches Ergebnis, so sieht es die Hauptautorin der Studie, Gaby Andersen: Es zeige, dass man mit üblichen Ingwermengen das Immunsystem modulieren könne. Additionally, the shortcomings in the current ginger clinical trials across domains need to be specified. The remaining papers were screened for title and abstract. Collectively, ginger has a beneficial effect on colorectal cancer by reducing tumorigenic risk factors. belongs to the family Zingiberaceae. Ginger treatment significantly increased milk volume on the third day compared to the placebo group. Pillai A.K., Sharma K.K., Gupta Y.K., Bakhshi S. Anti-emetic effect of ginger powder versus placebo as an add-on therapy in children and young adults receiving high emetogenic chemotherapy. compared the effects of sumatriptan and placebo, respectively, both showing there was a significant difference in symptom attenuation (p < 0.05) [23,66]. Bei neuen Testreihen im Labor haben die Forschenden nun untersucht, wie sich Gingerol auf Immunzellen auswirkt. Demographics and RCT designs from the studies that were evaluated to have a ‘high quality of evidence’ are described in Table 1. Efficacy of ginger in ameliorating acute and delayed chemotherapy-induced nausea and vomiting among patients with lung cancer receiving cisplatin-based regimens: A randomized controlled trial. This study aimed to provide a systematic summarization of the effectiveness of oral ginger in human health and diseases in current RCTs. Mandal P., Das A., Majumdar S., Bhattacharyya T., Mitra T., Kundu R. The efficacy of ginger added to ondansetron for preventing postoperative nausea and vomiting in ambulatory surgery. Das Team konnte die Andockstelle in bestimmten Zellen nachweisen: Die sogenannten neutrophilen Granulozyten machen etwa zwei Drittel der weißen Blutkörperchen aus und dienen dazu, eindringende Bakterien abzuwehren. Manche Menschen mögen den fruchtig-scharfen Geschmack, andere setzen darauf, dass Ingwertee ihre Abwehrkräfte stärkt. This result was supported by the biological property of ginger’s constituents inhibiting cyclooxygenase, which has a role in gastric mucosal defense [9,72]. All studies reported improvement following ginger intake compared to the control group. Thus, additional study is needed to make a conclusion. Use of ginger versus stretching exercises for the treatment of primary dysmenorrhea: A randomized controlled trial. Black C.D., O’Connor P.J. However, it had no significant difference in decreasing the number of vomiting episodes. Einige von ihnen sind notwendig zum Betrieb der Webseite und können nicht ausgeschaltet werden. Next, the titles and abstracts of the remaining records were screened for eligibility for the extraction process. Altogether, the analgesic effect of ginger on primary dysmenorrhea is worthy of consideration, but more appropriately designed studies should be conducted because the overall quality of the studies was not high. Neutrophile Granulozyten sind weiße Blutkörperchen (Leukozyten). Ginger treatment reduced menstrual blood loss significantly during three interventions. This may be an indicative result from the previously known mechanisms of ginger’s active compounds to suppress cyclooxygenase and lipoxygenase [9,72]. Ingwer und Zitrone sollen gut fürs Immunsystem sein. As an extension of the antiemetic property, ginger has been studied for its protective effect on the gastrointestinal system. Seventeen studies provided information about adverse effects in their research papers, most of which were not considered to be severely harmful to the participants. Ginger treatment reduced the frequency of vomiting and nausea significantly. „Doch die von außen so unscheinbare Wurzel verbirgt in ihrem Inneren auch eine breite Palette an medizinisch wirksamen Inhaltsstoffen und ist damit ein in der Naturheilkunde gerne verwendetes Heilmittel“, erklärt Dr. Roman Huber, Leiter des Uni-Zentrums Naturheilkunde. Der Gastroenterologe von der Charité hat an der aktuellen S2K-Leitinie „Zöliakie“ mitgewirkt und weiß, wodurch sich die Zöliakie von anderen Glutenunverträglichkeiten unterscheidet. 22.6.2022 The effects of ginger were reported in a variety of diseases and health conditions. Die Wurzel enthält unter anderem Eisen, Vitamine, Kalzium und Kalium, doch medizinisch bedeutsam sind vor allem zwei Gruppen von Inhaltsstoffen, erklärt Matthias Melzig, Professor für Biologische Pharmazie an der FU Berlin. Panahi Y., Saadat A., Sahebkar A., Hashemian F., Taghikhani M., Abolhasani E. Effect of ginger on acute and delayed chemotherapy-induced nausea and vomiting: A pilot, randomized, open-label clinical trial. The workflow of systematical search on ginger randomized clinical trials (RCTs) with five categorized substantial functions. Finally, only eight studies were judged as having low risks for every type of bias based on the Cochrane Collaboration’s quality assessment tool [14,18,20,28,29,31,45,55]. [58,59,60,61]. In addition, other potential effects are also briefly summarized and discussed. The types of adverse effects, incidence rate, and dosage are described in Table S4. DAZ.online ist der unabhängige tagesaktuelle Newsbereich für alle Apotheker und pharmazeutischen Berufsgruppen sowie an Gesundheitspolitik und evidenzbasierter Pharmazie interessierte Leser. Durch den Verzehr der würzigen Knolle setzt der Körper mehr Stoffe frei, die das Immunsystem stärken und fördern. There were differences in pain after administration in the ginger and zinc sulfate groups, and when compared with placebo groups, it was shown to be effective in both groups. Accordingly, 109 eligible papers were fully extracted in terms of study design, population characteristics, evaluation systems, adverse effects, and main outcomes. Incidence and severity of CINV by the MASCC Antiemesis Tool. Konmun J., Danwilai K., Ngamphaiboon N., Sripanidkulchai B., Sookprasert A., Subongkot S. A phase II randomized double-blind placebo-controlled study of 6-gingerol as an anti-emetic in solid tumor patients receiving moderately to highly emetogenic chemotherapy. Ebrahimzadeh Attari V., Asghari Jafarabadi M., Zemestani M., Ostadrahimi A. Thirty-six studies described the allocation concealment method with detailed explanations, and ten studies that provided ambiguous information about allocation were assigned to having an unclear risk. Overall, eight RCTs reported the anti-inflammatory effect of ginger supplementation. Biswas S.C., Dey R., Kamliya G.S., Bal R., Hazra A., Tripathi S. A single-masked, randomized, controlled trial of ginger extract in the treatment of nausea and vomiting of pregnancy. In terms of respiratory function, acute respiratory distress syndrome (ARDS) and asthma were examined to evaluate the improvement of symptoms. 609 Charles E. Young Drive, East Doch das stimmt nur teilweise. Marx W., Ried K., McCarthy A.L., Vitetta L., Sali A., McKavanagh D., Isenring L. Ginger—Mechanism of action in chemotherapy-induced nausea and vomiting: A review. As a result, many related biological activities have been explored such as those of antioxidant, antimicrobial, and anti-neuroinflammation, just to name a few [8]. Schon in einer früheren Studie konnte das Münchner Forschungsteam zeigen, dass Ingwertee nach 30 bis 60 Minuten die Blutwerte verändert. Moreover, several systematic reviews and meta-analysis (SR–MA), which aimed to assess the clinical ginger effectiveness, have been completed. Bliddal H., Rosetzsky A., Schlichting P., Weidner M.S., Andersen L.A., Ibfelt H.H., Christensen K., Jensen O.N., Barslev J. Fischer-Rasmussen W., Kjaer S.K., Dahl C., Asping U. Ginger treatment of hyperemesis gravidarum. ), 500 mg of wheat flour/cap, 4 capsules/day, 1 g of powdered ginger/tab, 2 tablets/day, 1 g of corn starch and other excipients/tab, 2tablets/day, 750 mg of powdered ginger/cap, 2 capsules/day, 750 mg of wheat flour/cap, 2 capsules/day, 43 (1st month); 41 (2nd month); 38 (3rd month), 0/43 (1st month) 0/41 (2nd month) 0/38 (3rd month), 250 mg of powdered ginger/cap, 3 capsules/day, 43 (1st month); 38 (2nd month); 33 (3rd month), 0/43 (1st month) 0/38 (2nd month) 0/33 (3rd month), From the day before menstrual bleeding to the 3rd day of the menstrual period, Breast milk volume of postpartum women who delivered a term baby (≥37 weeks of gestation), 500 mg of corn starch/cap, 2 capsules/day, One ginger capsule (250 mg of ginger extract) + 2 placebo capsules, twice/day, Two ginger capsules (250 mg of ginger extract) + 1 placebo capsule, twice/day, Three ginger capsules (250 mg of ginger extract), twice/day, 250 mg of dry ginger root extract/cap, 4 ginger capsules and 4 lactose capsules/day, 250 mg of dry ginger root extract/cap, 8 capsules/day, 250 mg of powdered ginger/cap, 2 capsules/day, 250 mg of powdered ginger/cap, 4 capsules/day, 6 days from three days before a chemotherapy session, 125 mg of ginger extract/cap, 4 capsules/day, 4 capsules/day, each capsule containing soya bean oil, 250 mg of powdered ginger root/cap, 4 capsules/day, 350 mg of ginger/cap, 3 capsules/day, tid, 25 mg of vitamin B6/cap, 3 capsules/day, tid, 150 mg of dried ginger extract/tab, 3 tablets/day, 10 mg of doxylamine + 10 mg of pyridoxine/tab, 2 or 3 tablets/day, One capsule containing 500 mg of powdered ginger and one placebo capsule, Two capsules containing 500 mg of powdered ginger, 100 mg of ginger extract/cap, 1 ginger capsule + 1 placebo capsule/dose, Triple dose: before operation and 3 h and 6 h post operation, 100 mg of ginger extract/cap, 2 ginger capsules/dose, 0.5 g of powdered ginger/cap, 2 capsules/dose + 4 mg of ondansetron (i.v.

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